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BMCBI
2010
189views more  BMCBI 2010»
13 years 11 months ago
Efficient parallel and out of core algorithms for constructing large bi-directed de Bruijn graphs
Background: Assembling genomic sequences from a set of overlapping reads is one of the most fundamental problems in computational biology. Algorithms addressing the assembly probl...
Vamsi Kundeti, Sanguthevar Rajasekaran, Hieu Dinh,...
BMCBI
2008
138views more  BMCBI 2008»
13 years 11 months ago
CASCADE: a novel quasi all paths-based network analysis algorithm for clustering biological interactions
Background: Quantitative characterization of the topological characteristics of protein-protein interaction (PPI) networks can enable the elucidation of biological functional modu...
Woochang Hwang, Young-Rae Cho, Aidong Zhang, Mural...
BMCBI
2008
175views more  BMCBI 2008»
13 years 11 months ago
Synonym set extraction from the biomedical literature by lexical pattern discovery
Background: Although there are a large number of thesauri for the biomedical domain many of them lack coverage in terms and their variant forms. Automatic thesaurus construction b...
John McCrae, Nigel Collier
BMCBI
2008
90views more  BMCBI 2008»
13 years 11 months ago
Ortholog-based protein-protein interaction prediction and its application to inter-species interactions
Background: The rapid growth of protein-protein interaction (PPI) data has led to the emergence of PPI network analysis. Despite advances in high-throughput techniques, the intera...
Sheng-An Lee, Chen-hsiung Chan, Chi-Hung Tsai, Jin...
BMCBI
2008
133views more  BMCBI 2008»
13 years 11 months ago
Towards ontology-driven navigation of the lipid bibliosphere
Background: The indexing of scientific literature and content is a relevant and contemporary requirement within life science information systems. Navigating information available ...
Christopher J. O. Baker, Kanagasabai Rajaraman, We...