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BMCBI
2010
116views more  BMCBI 2010»
13 years 9 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
HPDC
2010
IEEE
13 years 10 months ago
GatorShare: a file system framework for high-throughput data management
Voluntary Computing systems or Desktop Grids (DGs) enable sharing of commodity computing resources across the globe and have gained tremendous popularity among scientific research...
Jiangyan Xu, Renato J. O. Figueiredo
HPDC
2007
IEEE
14 years 3 months ago
A fast topology inference: a building block for network-aware parallel processing
Adapting to the network is the key to achieving high performance for communication-intensive applications, including scientific computing, data intensive computing, and multicast...
Tatsuya Shirai, Hideo Saito, Kenjiro Taura
ICAC
2005
IEEE
14 years 2 months ago
Feedback-based Scheduling for Back-end Databases in Shared Dynamic Content Server Clusters
This paper introduces a self-configuring architecture for scaling the database tier of dynamic content web servers. We use a unified approach to load and fault management based ...
Gokul Soundararajan, Kaloian Manassiev, Jin Chen, ...
DEBU
2008
100views more  DEBU 2008»
13 years 9 months ago
WAVE: Automatic Verification of Data-Driven Web Services
Data-driven Web services, viewed broadly as interactive systems available on the Web for users and programs, provide the backbone for increasingly complex Web applications. While ...
Alin Deutsch, Victor Vianu