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BMCBI
2010
143views more  BMCBI 2010»
13 years 7 months ago
Learning gene regulatory networks from only positive and unlabeled data
Background: Recently, supervised learning methods have been exploited to reconstruct gene regulatory networks from gene expression data. The reconstruction of a network is modeled...
Luigi Cerulo, Charles Elkan, Michele Ceccarelli
BMCBI
2008
122views more  BMCBI 2008»
13 years 7 months ago
Grammar-based distance in progressive multiple sequence alignment
Background: We propose a multiple sequence alignment (MSA) algorithm and compare the alignment-quality and execution-time of the proposed algorithm with that of existing algorithm...
David J. Russell, Hasan H. Otu, Khalid Sayood
BMCBI
2010
100views more  BMCBI 2010»
13 years 7 months ago
Using genomic signatures for HIV-1 sub-typing
Background: Human Immunodeficiency Virus type 1 (HIV-1), the causative agent of Acquired Immune Deficiency Syndrome (AIDS), exhibits very high genetic diversity with different var...
Aridaman Pandit, Somdatta Sinha
BMCBI
2008
136views more  BMCBI 2008»
13 years 7 months ago
LOMA: A fast method to generate efficient tagged-random primers despite amplification bias of random PCR on pathogens
Background: Pathogen detection using DNA microarrays has the potential to become a fast and comprehensive diagnostics tool. However, since pathogen detection chips currently utili...
Wah-Heng Lee, Christopher W. Wong, Wan Yee Leong, ...
BMCBI
2008
158views more  BMCBI 2008»
13 years 7 months ago
Analyzing M-CSF dependent monocyte/macrophage differentiation: Expression modes and meta-modes derived from an independent compo
Background: The analysis of high-throughput gene expression data sets derived from microarray experiments still is a field of extensive investigation. Although new approaches and ...
Dominik Lutter, Peter Ugocsai, Margot Grandl, Evel...
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