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BMCBI
2006
109views more  BMCBI 2006»
13 years 8 months ago
Integrated analysis of gene expression by association rules discovery
Background: Microarray technology is generating huge amounts of data about the expression level of thousands of genes, or even whole genomes, across different experimental conditi...
Pedro Carmona-Saez, Monica Chagoyen, Andrés...
BMCBI
2008
135views more  BMCBI 2008»
13 years 8 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
BMCBI
2008
122views more  BMCBI 2008»
13 years 8 months ago
A practical comparison of two K-Means clustering algorithms
Background: Data clustering is a powerful technique for identifying data with similar characteristics, such as genes with similar expression patterns. However, not all implementat...
Gregory A. Wilkin, Xiuzhen Huang
BMCBI
2008
126views more  BMCBI 2008»
13 years 8 months ago
GeneChaser: Identifying all biological and clinical conditions in which genes of interest are differentially expressed
Background: The amount of gene expression data in the public repositories, such as NCBI Gene Expression Omnibus (GEO) has grown exponentially, and provides a gold mine for bioinfo...
Rong Chen, Rohan Mallelwar, Ajit Thosar, Shivkumar...
BMCBI
2006
138views more  BMCBI 2006»
13 years 8 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...