208 search results - page 37 / 42 » An evolutionary method for learning HMM structure: predictio... |
BMCBI
2006
13 years 7 months ago
2006
Background: Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may corr...
ICML
2007
IEEE
14 years 8 months ago
2007
IEEE
We present a new machine learning approach for 3D-QSAR, the task of predicting binding affinities of molecules to target proteins based on 3D structure. Our approach predicts bind...
BMCBI
2010
13 years 7 months ago
2010
Background: Biological networks offer us a new way to investigate the interactions among different components and address the biological system as a whole. In this paper, a revers...
BMCBI
2004
13 years 7 months ago
2004
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
BMCBI
2006
13 years 7 months ago
2006
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...