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AO
2007
119views more  AO 2007»
13 years 11 months ago
The model of roles within an ontology development tool: Hozo
One of the major goals of ontology is to represent properly the underlying conceptual structure of the messy world reflecting the reality as much as possible. Ontology building to...
Riichiro Mizoguchi, Eiichi Sunagawa, Kouji Kozaki,...
BMCBI
2010
176views more  BMCBI 2010»
13 years 11 months ago
Bayesian statistical modelling of human protein interaction network incorporating protein disorder information
Background: We present a statistical method of analysis of biological networks based on the exponential random graph model, namely p2-model, as opposed to previous descriptive app...
Svetlana Bulashevska, Alla Bulashevska, Roland Eil...
BMCBI
2010
179views more  BMCBI 2010»
13 years 11 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
BMCBI
2010
144views more  BMCBI 2010»
13 years 11 months ago
Identifying overrepresented concepts in gene lists from literature: a statistical approach based on Poisson mixture model
Background: Large-scale genomic studies often identify large gene lists, for example, the genes sharing the same expression patterns. The interpretation of these gene lists is gen...
Xin He, Moushumi Sen Sarma, Xu Ling, Brant W. Chee...
BMCBI
2010
115views more  BMCBI 2010»
13 years 11 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
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