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» An integrated Bayesian analysis of LOH and copy number data
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BMCBI
2010
136views more  BMCBI 2010»
13 years 11 months ago
An integrated Bayesian analysis of LOH and copy number data
Background: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleoti...
Paola M. V. Rancoita, Marcus Hutter, Francesco Ber...
IWANN
2009
Springer
14 years 5 months ago
Bayesian Joint Estimation of CN and LOH Aberrations
SNP-microarrays are able to measure simultaneously both copy number and genotype at several single nucleotide polymorphism positions. Combining the two data, it is possible to bett...
Paola M. V. Rancoita, Marcus Hutter, Francesco Ber...
BMCBI
2005
93views more  BMCBI 2005»
13 years 11 months ago
Identification of novel prognostic markers in cervical intraepithelial neoplasia using LDMAS (LOH Data Management and Analysis S
Background: Detection of Loss of Heterozygosity (LOH) is one of the most common molecular applications in the study of human diseases, in particular cancer. The technique is commo...
Rifat A. Hamoudi, Amina El-Hamidi, Ming-Qing Du
BMCBI
2008
98views more  BMCBI 2008»
13 years 11 months ago
Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios
Background: Illumina Infinium whole genome genotyping (WGG) arrays are increasingly being applied in cancer genomics to study gene copy number alterations and allele-specific aber...
Johan Staaf, Johan Vallon-Christersson, David Lind...
BMCBI
2008
131views more  BMCBI 2008»
13 years 11 months ago
Major copy proportion analysis of tumor samples using SNP arrays
Background: Single nucleotide polymorphisms (SNPs) are the most common genetic variations in the human genome and are useful as genomic markers. Oligonucleotide SNP microarrays ha...
Cheng Li, Rameen Beroukhim, Barbara A. Weir, Wendy...