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BMCBI
2011
13 years 2 months ago
ATAQS: A computational software tool for high throughput transition optimization and validation for selected reaction monitoring
Background: Since its inception, proteomics has essentially operated in a discovery mode with the goal of identifying and quantifying the maximal number of proteins in a sample. I...
Mi-Youn K. Brusniak, Sung-Tat Kwok, Mark Christian...
CSB
2005
IEEE
210views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Problem Solving Environment Approach to Integrating Diverse Biological Data Sources
Scientists face an ever-increasing challenge in investigating biological systems with high throughput experimental methods such as mass spectrometry and gene arrays because of the...
Eric G. Stephan, Kyle R. Klicker, Mudita Singhal, ...
ISMB
2007
13 years 10 months ago
A Chado case study: an ontology-based modular schema for representing genome-associated biological information
Motivation: A few years ago, FlyBase undertook to design a new database schema to store Drosophila data. It would fully integrate genomic sequence and annotation data with bibliog...
Chris Mungall, David B. Emmert
BMCBI
2010
138views more  BMCBI 2010»
13 years 8 months ago
A model-independent approach to infer hierarchical codon substitution dynamics
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...
Olof Görnerup, Martin Nilsson Jacobi
NAR
2006
100views more  NAR 2006»
13 years 7 months ago
StellaBase: The Nematostella vectensis Genomics Database
ted Talks and Poster Abstracts S1, T1 Title: Evolution of the Mammalian Lamin A Gene Author: Susan N. LoCurto and Dorothy E. Pumo Affiliation: Hofstra University, Department of Bio...
James C. Sullivan, Joseph F. Ryan, James A. Watson...