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» An integrative approach to modeling biological networks
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BMCBI
2010
150views more  BMCBI 2010»
13 years 7 months ago
Systematic calibration of a cell signaling network model
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...
BIBE
2009
IEEE
252views Bioinformatics» more  BIBE 2009»
14 years 2 months ago
Multi-Agents System to Model Cell Signalling by Using Fuzzy Cognitive Maps. Application to Computer Simulation of Multiple Myelo
—In order to simulate biological processes, we use multi-agents system. However, modelling cell behavior in systems biology is complex and may be based on intracellular biochemic...
Vincent Rodin, Gabriel Querrec, Pascal Ballet, Fra...
GPB
2010
231views Solid Modeling» more  GPB 2010»
13 years 5 months ago
Mining Gene Expression Profiles: An Integrated Implementation of Kernel Principal Component Analysis and Singular Value Decompos
The detection of genes that show similar profiles under different experimental conditions is often an initial step in inferring the biological significance of such genes. Visualiz...
Ferran Reverter, Esteban Vegas, Pedro Sánch...
AMC
2008
92views more  AMC 2008»
13 years 7 months ago
Bifurcation of nontrivial periodic solutions for an impulsively controlled pest management model
In this paper, we investigate the existence of nontrivial periodic solutions for an integrated pest management model which is impulsively controlled by means of biological and che...
Paul Georgescu, Hong Zhang, Lansun Chen
IJON
2006
123views more  IJON 2006»
13 years 7 months ago
A novel approach to model neuronal signal transduction using stochastic differential equations
We introduce a new approach to model the behavior of neuronal signal transduction networks using stochastic differential equations. We present first a mathematical formulation for...
Tiina Manninen, Marja-Leena Linne, Keijo Ruohonen