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» Analogue Circuit Control through Gene Expression
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ICASSP
2011
IEEE
13 years 9 days ago
Uncover cooperative gene regulations by microRNAs and transcription factors in glioblastoma using a nonnegative hybrid factor mo
—Transcriptional regulation by transcription factors (TFs) and microRNAs controls when and how much RNA is created. Due to technical limitations, the protein level expressions of...
Jia Meng, Hung-I Harry Chen, Jianqiu Zhang, Yidong...
BMCBI
2008
107views more  BMCBI 2008»
13 years 8 months ago
A mixture model approach to sample size estimation in two-sample comparative microarray experiments
Background: Choosing the appropriate sample size is an important step in the design of a microarray experiment, and recently methods have been proposed that estimate sample sizes ...
Tommy S. Jørstad, Herman Midelfart, Atle M....
BMCBI
2008
118views more  BMCBI 2008»
13 years 8 months ago
Kismeth: Analyzer of plant methylation states through bisulfite sequencing
Background: There is great interest in probing the temporal and spatial patterns of cytosine methylation states in genomes of a variety of organisms. It is hoped that this will sh...
Eyal Gruntman, Yijun Qi, R. Keith Slotkin, Ted Roe...
WSC
2007
13 years 11 months ago
Optimizing time warp simulation with reinforcement learning techniques
Adaptive Time Warp protocols in the literature are usually based on a pre-defined analytic model of the system, expressed as a closed form function that maps system state to cont...
Jun Wang, Carl Tropper
GECCO
2006
Springer
202views Optimization» more  GECCO 2006»
14 years 6 days ago
Inference of genetic networks using S-system: information criteria for model selection
In this paper we present an evolutionary approach for inferring the structure and dynamics in gene circuits from observed expression kinetics. For representing the regulatory inte...
Nasimul Noman, Hitoshi Iba