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BMCBI
2006
116views more  BMCBI 2006»
13 years 7 months ago
Cluster analysis for DNA methylation profiles having a detection threshold
Background: DNA methylation, a molecular feature used to investigate tumor heterogeneity, can be measured on many genomic regions using the MethyLight technology. Due to the combi...
Paul Marjoram, Jing Chang, Peter W. Laird, Kimberl...
BIBE
2007
IEEE
124views Bioinformatics» more  BIBE 2007»
14 years 1 months ago
Finding Cancer-Related Gene Combinations Using a Molecular Evolutionary Algorithm
—High-throughput data such as microarrays make it possible to investigate the molecular-level mechanism of cancer more efficiently. Computational methods boost the microarray ana...
Chan-Hoon Park, Soo-Jin Kim, Sun Kim, Dong-Yeon Ch...
GMP
2006
IEEE
108views Solid Modeling» more  GMP 2006»
14 years 1 months ago
Towards Unsupervised Segmentation of Semi-rigid Low-Resolution Molecular Surfaces
In this paper, we study a particular type of surface segmentation problem motivated by molecular biology applications. In particular, two input surfaces are given, coarsely modeli...
Yusu Wang, Leonidas J. Guibas
BMCBI
2008
160views more  BMCBI 2008»
13 years 7 months ago
Cross-species and cross-platform gene expression studies with the Bioconductor-compliant R package 'annotationTools'
Background: The variety of DNA microarray formats and datasets presently available offers an unprecedented opportunity to perform insightful comparisons of heterogeneous data. Cro...
Alexandre Kuhn, Ruth Luthi-Carter, Mauro Delorenzi
HIPC
2003
Springer
14 years 7 days ago
Performance Analysis of Blue Gene/L Using Parallel Discrete Event Simulation
High performance computers currently under construction, such as IBM’s Blue Gene/L, consisting of large numbers (64K) of low cost processing elements with relatively small local...
Ed Upchurch, Paul L. Springer, Maciej Brodowicz, S...