Insight to complex problems may be revealed when domain data sets are viewed or structured in new and innovative ways. Systems approaches to biomedical problems fundamentally invo...
Donald J. Johann, Michael D. McGuigan, Stanimire T...
Motivation: Peaks are the key information in Mass Spectrometry (MS) which has been increasingly used to discover diseases related proteomic patterns. Peak detection is an essentia...
Nha Nguyen, Heng Huang, Soontorn Oraintara, An P. ...
In this paper we present a method for clustering SAGE (Serial Analysis of Gene Expression) data to detect similarities and dissimilarities between different types of cancer on the...
Background: Bisulfite sequencing is a popular method to analyze DNA methylation patterns at high resolution. A region of interest is targeted by PCR and about 20-50 subcloned DNA ...
Christian Rohde, Yingying Zhang, Richard Reinhardt...
Background: Feature selection is a pattern recognition approach to choose important variables according to some criteria in order to distinguish or explain certain phenomena (i.e....