Background: The identification and characterization of genes that influence the risk of common, complex multifactorial disease primarily through interactions with other genes and ...
Alison A. Motsinger, Stephen L. Lee, George Mellic...
Background: Recent progresses in genotyping technologies allow the generation high-density genetic maps using hundreds of thousands of genetic markers for each DNA sample. The ava...
Studying the association between quantitative phenotype (such as height or weight) and single nucleotide polymorphisms (SNPs) is an important problem in biology. To understand und...
The study of common, complex multifactorial diseases in genetic epidemiology is complicated by nonlinearity in the genotype-to-phenotype mapping relationship that is due, in part,...
Ryan J. Urbanowicz, Nate Barney, Bill C. White, Ja...
Background: Finding the genetic causes of quantitative traits is a complex and difficult task. Classical methods for mapping quantitative trail loci (QTL) in miceuse an F2 cross b...
Phillip McClurg, Mathew T. Pletcher, Tim Wiltshire...