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BMCBI
2010
169views more  BMCBI 2010»
13 years 7 months ago
eCOMPAGT integrates mtDNA: import, validation and export of mitochondrial DNA profiles for population genetics, tumour dynamics
Background: Mitochondrial DNA (mtDNA) is widely being used for population genetics, forensic DNA fingerprinting and clinical disease association studies. The recent past has uncov...
Hansi Weißensteiner, Sebastian Schönher...
BMCBI
2010
115views more  BMCBI 2010»
13 years 7 months ago
CONAN: copy number variation analysis software for genome-wide association studies
Background: Genome-wide association studies (GWAS) based on single nucleotide polymorphisms (SNPs) revolutionized our perception of the genetic regulation of complex traits and di...
Lukas Forer, Sebastian Schönherr, Hansi Wei&s...
ICMLA
2008
13 years 8 months ago
Target Selection: A New Learning Paradigm and Its Application to Genetic Association Studies
In this work, a new learning paradigm called target selection is proposed, which can be used to test for associations between a single genetic variable and a multidimensional, qua...
Johannes Mohr, Sambu Seo, Imke Puis, Andreas Heinz...
CEC
2009
IEEE
14 years 2 months ago
Optimization of the sizing of a solar thermal electricity plant: Mathematical programming versus genetic algorithms
— Genetic algorithms (GAs) have been argued to constitute a flexible search thereby enabling to solve difficult problems which classical optimization methodologies may find ha...
Jose M. Cabello, Jose M. Cejudo, Mariano Luque, Fr...
BMCBI
2008
128views more  BMCBI 2008»
13 years 7 months ago
HAPSIMU: a genetic simulation platform for population-based association studies
Background: Population structure is an important cause leading to inconsistent results in population-based association studies (PBAS) of human diseases. Various statistical method...
Feng Zhang, Jianfeng Liu, Jie Chen, Hong-Wen Deng