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BMCBI
2010
189views more  BMCBI 2010»
13 years 7 months ago
High quality protein sequence alignment by combining structural profile prediction and profile alignment using SABERTOOTH
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
Florian Teichert, Jonas Minning, Ugo Bastolla, Mar...
BMCBI
2010
156views more  BMCBI 2010»
13 years 7 months ago
Protein complex prediction via verifying and reconstructing the topology of domain-domain interactions
Background: High-throughput methods for detecting protein-protein interactions enable us to obtain large interaction networks, and also allow us to computationally identify the as...
Yosuke Ozawa, Rintaro Saito, Shigeo Fujimori, Hisa...
BIOCOMP
2006
13 years 9 months ago
A Multi-strategy Approach to Protein Structural Alphabet Design
- The search for structural similarity among proteins can provide valuable insights into their functional mechanisms and their functional relationships. Though the protein 1D seque...
Shih-Yen Ku, Yuh-Jyh Hu
GCB
2007
Springer
161views Biometrics» more  GCB 2007»
14 years 1 months ago
High-Precision Function Prediction using Conserved Interactions
: The recent availability of large data sets of protein- protein-interactions (PPIs) from various species offers new opportunities for functional genomics and proteomics. We descri...
Samira Jaeger, Ulf Leser
BIRD
2007
Springer
112views Bioinformatics» more  BIRD 2007»
14 years 1 months ago
Patch Prediction of Protein Interaction Sites: Validation of a Scoring Function for an Online Server
An online protein interaction server has been designed and implemented to make predictions for 256 nonhomologous protein-protein interaction sites using patch analysis. Predictions...
Susan Jones, Yoichi Mukarami