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BMCBI
2008
104views more  BMCBI 2008»
13 years 7 months ago
Evolutionary Pareto-optimization of stably folding peptides
Background: As a rule, peptides are more flexible and unstructured than proteins with their substantial stabilizing hydrophobic cores. Nevertheless, a few stably folding peptides ...
Wolfram Gronwald, Tim Hohm, Daniel Hoffmann
BMCBI
2008
220views more  BMCBI 2008»
13 years 7 months ago
Gene prediction in metagenomic fragments: A large scale machine learning approach
Background: Metagenomics is an approach to the characterization of microbial genomes via the direct isolation of genomic sequences from the environment without prior cultivation. ...
Katharina J. Hoff, Maike Tech, Thomas Lingner, Rol...
WABI
2005
Springer
120views Bioinformatics» more  WABI 2005»
14 years 1 months ago
Multiple Structural RNA Alignment with Lagrangian Relaxation
In contrast to proteins, many classes of functionally related RNA molecules show a rather weak sequence conservation but instead a fairly well conserved secondary structure. Hence ...
Markus Bauer, Gunnar W. Klau, Knut Reinert
CIKM
2009
Springer
14 years 2 months ago
Completing wikipedia's hyperlink structure through dimensionality reduction
Wikipedia is the largest monolithic repository of human knowledge. In addition to its sheer size, it represents a new encyclopedic paradigm by interconnecting articles through hyp...
Robert West, Doina Precup, Joelle Pineau
CCECE
2006
IEEE
14 years 1 months ago
Evaluation of RNA Secondary Structure Motifs using Regression Analysis
Recent experimental evidences have shown that ribonucleic acid (RNA) plays a greater role in the cell than previously thought. An ensemble of RNA sequences believed to contain sig...
Mohammad Anwar, Marcel Turcotte