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BMCBI
2006
127views more  BMCBI 2006»
13 years 7 months ago
Improvement in the Reproducibility and Accuracy of DNA Microarray Quantification by Optimizing Hybridization Conditions
Background: DNA microarrays, which have been increasingly used to monitor mRNA transcripts at a global level, can provide detailed insight into cellular processes involved in resp...
Tao Han, Cathy D. Melvin, Leming M. Shi, William S...
ISMB
2000
13 years 8 months ago
Analysis of Gene Expression Microarrays for Phenotype Classification
Several microarray technologies that monitor the level of expression of a large number of genes have recently emerged. Given DNA-microarray data for a set of cells characterized b...
Andrea Califano, Gustavo Stolovitzky, Yuhai Tu
BIOINFORMATICS
2010
170views more  BIOINFORMATICS 2010»
13 years 7 months ago
Joint estimation of DNA copy number from multiple platforms
DNA copy number variants (CNV) are gains and losses of segments of chromosomes, and comprise an important class of genetic variation. Recently, various microarray hybridization ba...
Nancy R. Zhang, Yasin Senbabaoglu, Jun Z. Li
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
Biologically relevant effects of mRNA amplification on gene expression profiles
Background: Gene expression microarray technology permits the analysis of global gene expression profiles. The amount of sample needed limits the use of small excision biopsies an...
Rachel I. M. van Haaften, Blanche Schroen, Ben J. ...
BMCBI
2011
13 years 2 months ago
Empirical Bayesian models for analysing molecular serotyping microarrays
Background: Microarrays offer great potential as a platform for molecular diagnostics, testing clinical samples for the presence of numerous biomarkers in highly multiplexed assay...
Richard Newton, Jason Hinds, Lorenz Wernisch