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BMCBI
2004
154views more  BMCBI 2004»
13 years 7 months ago
Computation of elementary modes: a unifying framework and the new binary approach
Background: Metabolic pathway analysis has been recognized as a central approach to the structural analysis of metabolic networks. The concept of elementary (flux) modes provides ...
Julien Gagneur, Steffen Klamt
BMCBI
2004
228views more  BMCBI 2004»
13 years 7 months ago
An XML standard for the dissemination of annotated 2D gel electrophoresis data complemented with mass spectrometry results
Background: Many proteomics initiatives require a seamless bioinformatics integration of a range of analytical steps between sample collection and systems modeling immediately ass...
Romesh Stanislaus, Liu Hong Jiang, Martha Swartz, ...
BMCBI
2004
139views more  BMCBI 2004»
13 years 7 months ago
Resolution of large and small differences in gene expression using models for the Bayesian analysis of gene expression levels an
Background: The detection of small yet statistically significant differences in gene expression in spotted DNA microarray studies is an ongoing challenge. Meeting this challenge r...
Jeffrey P. Townsend
JUCS
2000
102views more  JUCS 2000»
13 years 6 months ago
Towards Two-Level Formal Modeling of Computer-Based Systems
: Embedded Computer-based Systems are becoming highly complex and hard to implement because of the large number of concerns the designers have to address. These systems are tightly...
Gabor Karsai, Greg Nordstrom, Ákos Lé...
IEEEMM
2002
134views more  IEEEMM 2002»
13 years 6 months ago
A Middleware Architecture for Open and Interoperable GISs
an abstract model for information sharing and integration and use it to develop an architecture for building open, component-based, interoperable systems. A geographic information ...
Steven H. Wong, Steven L. Swartz, Dilip Sarkar