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BMCBI
2010
135views more  BMCBI 2010»
13 years 7 months ago
Lists2Networks: Integrated analysis of gene/protein lists
Background: Systems biologists are faced with the difficultly of analyzing results from large-scale studies that profile the activity of many genes, RNAs and proteins, applied in ...
Alexander Lachmann, Avi Ma'ayan
BMCBI
2010
165views more  BMCBI 2010»
13 years 7 months ago
Bayesian integrated modeling of expression data: a case study on RhoG
Background: DNA microarrays provide an efficient method for measuring activity of genes in parallel and even covering all the known transcripts of an organism on a single array. T...
Rashi Gupta, Dario Greco, Petri Auvinen, Elja Arja...
BMCBI
2010
115views more  BMCBI 2010»
13 years 7 months ago
CONAN: copy number variation analysis software for genome-wide association studies
Background: Genome-wide association studies (GWAS) based on single nucleotide polymorphisms (SNPs) revolutionized our perception of the genetic regulation of complex traits and di...
Lukas Forer, Sebastian Schönherr, Hansi Wei&s...
BMCBI
2010
77views more  BMCBI 2010»
13 years 7 months ago
web cellHTS2: A web-application for the analysis of high-throughput screening data
Background: The analysis of high-throughput screening data sets is an expanding field in bioinformatics. Highthroughput screens by RNAi generate large primary data sets which need...
Oliver Pelz, Moritz Gilsdorf, Michael Boutros
BMCBI
2010
144views more  BMCBI 2010»
13 years 7 months ago
Identifying overrepresented concepts in gene lists from literature: a statistical approach based on Poisson mixture model
Background: Large-scale genomic studies often identify large gene lists, for example, the genes sharing the same expression patterns. The interpretation of these gene lists is gen...
Xin He, Moushumi Sen Sarma, Xu Ling, Brant W. Chee...