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» Analyzing symmetry in biological systems
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BMCBI
2008
105views more  BMCBI 2008»
13 years 7 months ago
SIGMA2: A system for the integrative genomic multi-dimensional analysis of cancer genomes, epigenomes, and transcriptomes
Background: High throughput microarray technologies have afforded the investigation of genomes, epigenomes, and transcriptomes at unprecedented resolution. However, software packa...
Raj Chari, Bradley P. Coe, Craig Wedseltoft, Marie...
QEST
2007
IEEE
14 years 1 months ago
Probabilistic Model Checking Modulo Theories
— Probabilistic models are widely used to analyze embedded, networked, and more recently biological systems. Existing numerical analysis techniques are limited to finitestate mo...
Björn Wachter, Lijun Zhang, Holger Hermanns
SAC
2009
ACM
14 years 2 months ago
GTfold: a scalable multicore code for RNA secondary structure prediction
The prediction of the correct secondary structures of large RNAs is one of the unsolved challenges of computational molecular biology. Among the major obstacles is the fact that a...
Amrita Mathuriya, David A. Bader, Christine E. Hei...
BMCBI
2005
112views more  BMCBI 2005»
13 years 7 months ago
Towards precise classification of cancers based on robust gene functional expression profiles
Background: Development of robust and efficient methods for analyzing and interpreting high dimension gene expression profiles continues to be a focus in computational biology. Th...
Zheng Guo, Tianwen Zhang, Xia Li, Qi Wang, Jianzhe...
RECOMB
2002
Springer
14 years 8 months ago
Deconvolving sequence variation in mixed DNA populations
We present an original approach to identifying sequence variants in a mixed DNA population from sequence trace data. The heart of the method is based on parsimony: given a wildtyp...
Andy Wildenberg, Steven Skiena, Pavel Sumazin