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BIOINFORMATICS
2007
137views more  BIOINFORMATICS 2007»
13 years 7 months ago
Annotation-based distance measures for patient subgroup discovery in clinical microarray studies
: Background Clustering algorithms are widely used in the analysis of microarray data. In clinical studies, they are often applied to find groups of co-regulated genes. Clustering...
Claudio Lottaz, Joern Toedling, Rainer Spang
BMCBI
2010
130views more  BMCBI 2010»
13 years 7 months ago
Knowledge-guided gene ranking by coordinative component analysis
Background: In cancer, gene networks and pathways often exhibit dynamic behavior, particularly during the process of carcinogenesis. Thus, it is important to prioritize those gene...
Chen Wang, Jianhua Xuan, Huai Li, Yue Wang, Ming Z...
BIBM
2008
IEEE
107views Bioinformatics» more  BIBM 2008»
14 years 1 months ago
A Functional Network of Yeast Genes Using Gene Ontology Information
In the post-genomic era, the organization of genes into networks has played an important role in characterizing the functions of individual genes and the interplay between them. I...
Erliang Zeng, Giri Narasimhan, Lisa Schneper, Kala...
BMCBI
2008
126views more  BMCBI 2008»
13 years 7 months ago
c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
Katerina Kechris, Hao Li
BIBE
2007
IEEE
153views Bioinformatics» more  BIBE 2007»
13 years 9 months ago
Combined expression data with missing values and gene interaction network analysis: a Markovian integrated approach
—DNA microarray technologies provide means for monitoring in the order of tens of thousands of gene expression levels quantitatively and simultaneously. However data generated in...
Juliette Blanchet, Matthieu Vignes