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BMCBI
2010
102views more  BMCBI 2010»
13 years 7 months ago
SAMPLEX: Automatic mapping of perturbed and unperturbed regions of proteins and complexes
Background: The activity of proteins within the cell is characterized by their motions, flexibility, interactions or even the particularly intriguing case of partially unfolded st...
Mickaël Krzeminski, Karine Loth, Rolf Boelens...
BMCBI
2010
109views more  BMCBI 2010»
13 years 7 months ago
ParallABEL: an R library for generalized parallelization of genome-wide association studies
Background: Genome-Wide Association (GWA) analysis is a powerful method for identifying loci associated with complex traits and drug response. Parts of GWA analyses, especially th...
Unitsa Sangket, Surakameth Mahasirimongkol, Wasun ...
BMCBI
2010
183views more  BMCBI 2010»
13 years 7 months ago
SOPRA: Scaffolding algorithm for paired reads via statistical optimization
Background: High throughput sequencing (HTS) platforms produce gigabases of short read (<100 bp) data per run. While these short reads are adequate for resequencing application...
Adel Dayarian, Todd P. Michael, Anirvan M. Sengupt...
BMCBI
2010
117views more  BMCBI 2010»
13 years 7 months ago
New decoding algorithms for Hidden Markov Models using distance measures on labellings
Background: Existing hidden Markov model decoding algorithms do not focus on approximately identifying the sequence feature boundaries. Results: We give a set of algorithms to com...
Daniel G. Brown 0001, Jakub Truszkowski
BMCBI
2008
122views more  BMCBI 2008»
13 years 7 months ago
Grammar-based distance in progressive multiple sequence alignment
Background: We propose a multiple sequence alignment (MSA) algorithm and compare the alignment-quality and execution-time of the proposed algorithm with that of existing algorithm...
David J. Russell, Hasan H. Otu, Khalid Sayood
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