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BMCBI
2010
105views more  BMCBI 2010»
15 years 5 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
BMCBI
2010
122views more  BMCBI 2010»
15 years 5 months ago
An overview of the CellML API and its implementation
Background: CellML is an XML based language for representing mathematical models, in a machine-independent form which is suitable for their exchange between different authors, and...
Andrew K. Miller, Justin Marsh, Adam Reeve, Alan G...
BMCBI
2008
166views more  BMCBI 2008»
15 years 5 months ago
Biclustering via optimal re-ordering of data matrices in systems biology: rigorous methods and comparative studies
Background: The analysis of large-scale data sets via clustering techniques is utilized in a number of applications. Biclustering in particular has emerged as an important problem...
Peter A. DiMaggio Jr., Scott R. McAllister, Christ...
BMCBI
2008
83views more  BMCBI 2008»
15 years 5 months ago
Terminologies for text-mining; an experiment in the lipoprotein metabolism domain
Background: The engineering of ontologies, especially with a view to a text-mining use, is still a new research field. There does not yet exist a well-defined theory and technolog...
Dimitra Alexopoulou, Thomas Wächter, Laura Pi...
CN
2008
140views more  CN 2008»
15 years 5 months ago
Congestion control in utility fair networks
This paper deals with a congestion control framework for elastic and real-time traffic, where the user's application is associated with a utility function. We allow users to ...
Tobias Harks, Tobias Poschwatta