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BMCBI
2006
129views more  BMCBI 2006»
13 years 8 months ago
Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...
Tomas Ohlson, Varun Aggarwal, Arne Elofsson, Rober...
SC
2003
ACM
14 years 1 months ago
A Million-Fold Speed Improvement in Genomic Repeats Detection
This paper presents a novel, parallel algorithm for generating top alignments. Top alignments are used for finding internal repeats in biological sequences like proteins and gene...
John W. Romein, Jaap Heringa, Henri E. Bal
BMCBI
2010
139views more  BMCBI 2010»
13 years 8 months ago
CMASA: an accurate algorithm for detecting local protein structural similarity and its application to enzyme catalytic site anno
Background: The rapid development of structural genomics has resulted in many "unknown function" proteins being deposited in Protein Data Bank (PDB), thus, the functiona...
Gong-Hua Li, Jing-Fei Huang
CANDC
2006
ACM
13 years 8 months ago
Prediction of protein subcellular location using hydrophobic patterns of amino acid sequence
The function of eukaryotic protein is closely correlated with its subcellular location. The number of newly found protein sequences entering into data banks is rapidly increasing ...
Tongliang Zhang, Yongsheng Ding, Kuo-Chen Chou
BMCBI
2005
92views more  BMCBI 2005»
13 years 7 months ago
Predicting functional sites with an automated algorithm suitable for heterogeneous datasets
Background: In a previous report (La et al., Proteins, 2005), we have demonstrated that the identification of phylogenetic motifs, protein sequence fragments conserving the overal...
David La, Dennis R. Livesay