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GCB
2010
Springer
198views Biometrics» more  GCB 2010»
13 years 5 months ago
RNALfoldz: Efficient Prediction of Thermodynamically Stable, Local Secondary Structures
Abstract: The search for local RNA secondary structures and the annotation of unusually stable folding regions in genomic sequences are two well motivated bioinformatic problems. I...
Andreas R. Gruber, Stephan H. F. Bernhart, You Zho...
JCB
2000
101views more  JCB 2000»
13 years 7 months ago
Evaluation Measures of Multiple Sequence Alignments
Multiple sequence alignments (MSAs) are frequently used in the study of families of protein sequences or DNA/RNA sequences. They are a fundamental tool for the understanding of th...
Gaston H. Gonnet, Chantal Korostensky, Steven A. B...
CEC
2010
IEEE
13 years 9 months ago
A parallel framework for multi-objective evolutionary optimization
This work focuses on the development of a parallel framework method to improve the effectiveness and the efficiency of the obtained solutions by Multi-objective Evolutionary Algori...
Dipankar Dasgupta, David Camilo Becerra Romero, Al...
PRIB
2010
Springer
123views Bioinformatics» more  PRIB 2010»
13 years 6 months ago
Machine Learning Study of DNA Binding by Transcription Factors from the LacI Family
We studied 1372 LacI-family transcription factors and their 4484 DNA binding sites using machine learning algorithms and feature selection techniques. The Naive Bayes classifier a...
Gennady G. Fedonin, Mikhail S. Gelfand
BMCBI
2010
158views more  BMCBI 2010»
13 years 8 months ago
Validation of differential gene expression algorithms: Application comparing fold-change estimation to hypothesis testing
Background: Sustained research on the problem of determining which genes are differentially expressed on the basis of microarray data has yielded a plethora of statistical algorit...
Corey M. Yanofsky, David R. Bickel