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BMCBI
2008
13 years 7 months ago
2008
Background: We have previously described an approach to predicting the substrate specificity of serine-threonine protein kinases. The method, named Predikin, identifies key conser...
BMCBI
2008
13 years 7 months ago
2008
Background: DNA microarrays contain thousands of different probe sequences represented on their surface. These are designed in such a way that potential cross-hybridization reacti...
BMCBI
2008
13 years 7 months ago
2008
Background: Computational discovery of motifs in biomolecular sequences is an established field, with applications both in the discovery of functional sites in proteins and regula...
BMCBI
2008
13 years 7 months ago
2008
Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
BMCBI
2008
13 years 7 months ago
2008
Background: The Clinical E-Science Framework (CLEF) project has built a system to extract clinically significant information from the textual component of medical records in order...