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NAR
2007
132views more  NAR 2007»
13 years 8 months ago
TRED: a transcriptional regulatory element database, new entries and other development
Transcriptional factors (TFs) and many of their target genes are involved in gene regulation at the level of transcription. To decipher gene regulatory networks (GRNs) we require ...
C. Jiang, Zhenyu Xuan, Fang Zhao, Michael Q. Zhang
BIOINFORMATICS
2006
129views more  BIOINFORMATICS 2006»
13 years 8 months ago
Predicting methylation status of CpG islands in the human brain
Motivation: Over 50% of human genes contain CpG islands in their 5'-regions. Methylation patterns of CpG islands are involved in tissue-specific gene expression and regulatio...
Fang Fang, Shicai Fan, Xuegong Zhang, Michael Q. Z...
BMCBI
2010
151views more  BMCBI 2010»
13 years 8 months ago
Classification of G-protein coupled receptors based on support vector machine with maximum relevance minimum redundancy and gene
Background: Because a priori knowledge about function of G protein-coupled receptors (GPCRs) can provide useful information to pharmaceutical research, the determination of their ...
Zhanchao Li, Xuan Zhou, Zong Dai, Xiaoyong Zou
BMCBI
2011
13 years 3 months ago
Support vector machines-based identification of alternative splicing in Arabidopsis thaliana from whole-genome tiling arrays
Background: Alternative splicing (AS) is a process which generates several distinct mRNA isoforms from the same gene by splicing different portions out of the precursor transcript...
Johannes Eichner, Georg Zeller, Sascha Laubinger, ...
BMCBI
2008
102views more  BMCBI 2008»
13 years 8 months ago
Fast splice site detection using information content and feature reduction
Background: Accurate identification of splice sites in DNA sequences plays a key role in the prediction of gene structure in eukaryotes. Already many computational methods have be...
A. K. M. A. Baten, Saman K. Halgamuge, Bill C. H. ...