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» Approximate Global Alignment of Sequences
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ALMOB
2008
82views more  ALMOB 2008»
13 years 8 months ago
Protein sequence and structure alignments within one framework
Background: Protein structure alignments are usually based on very different techniques to sequence alignments. We propose a method which treats sequence, structure and even combi...
Gundolf Schenk, Thomas Margraf, Andrew E. Torda
AAAI
2000
13 years 10 months ago
Divide-and-Conquer Frontier Search Applied to Optimal Sequence Alignment
We present a new algorithm that reduces the space complexity of heuristic search. It is most effective for problem spaces that grow polynomially with problem size, but contain lar...
Richard E. Korf, Weixiong Zhang
BMCBI
2004
158views more  BMCBI 2004»
13 years 8 months ago
Improvement of alignment accuracy utilizing sequentially conserved motifs
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...
Saikat Chakrabarti, Nitin Bhardwaj, Prem A. Anand,...
GCB
2004
Springer
139views Biometrics» more  GCB 2004»
14 years 2 months ago
Graph Alignments: A New Concept to Detect Conserved Regions in Protein Active Sites
: We introduce the novel concept of graph alignment, a generalization of graph isomorphism that is motivated by the commonly used multiple sequence alignments. Graph alignments and...
Nils Weskamp, Eyke Hüllermeier, Daniel Kuhn, ...
BIOINFORMATICS
2005
75views more  BIOINFORMATICS 2005»
13 years 8 months ago
DbW: automatic update of a functional family-specific multiple alignment
: Recent advances in gene sequencing have provided complete sequence information for a number of genomes and as a result the amount of data in the sequence databases is growing at ...
Veronique Prigent, Jean-Claude Thierry, Olivier Po...