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ALMOB
2008
13 years 7 months ago
2008
Background: It is of biological interest to make genome-wide predictions of the locations of DNA melting bubbles using statistical mechanics models. Computationally, this poses th...
BMCBI
2010
13 years 7 months ago
2010
Background: Theme-driven cancer survival studies address whether the expression signature of genes related to a biological process can predict patient survival time. Although this...
BMCBI
2010
13 years 7 months ago
2010
Background: In many microarray experiments, analysis is severely hindered by a major difficulty: the small number of samples for which expression data has been measured. When one ...
BMCBI
2008
13 years 7 months ago
2008
Background: Testing for selection is becoming one of the most important steps in the analysis of multilocus population genetics data sets. Existing applications are difficult to u...
BMCBI
2008
13 years 7 months ago
2008
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...