Background: Most non-coding RNA families exert their function by means of a conserved, common secondary structure. The Rfam data base contains more than five hundred structurally ...
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....
Background: Growing interest in the application of natural language processing methods to biomedical text has led to an increasing number of corpora and methods targeting protein-...
Sampo Pyysalo, Antti Airola, Juho Heimonen, Jari B...
This paper proposes a new concept of polycube splines and develops novel modeling techniques for using the polycube splines in solid modeling and shape computing. Polycube splines...
Hongyu Wang, Ying He 0001, Xin Li, Xianfeng Gu, Ho...
The MUSIC algorithm, and its extension for imaging sparse extended objects, with noisy data is analyzed by compressed sensing (CS) techniques. A thresholding rule is developed to a...