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» Approximating the Number of Network Motifs
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ALMOB
2006
138views more  ALMOB 2006»
13 years 7 months ago
A combinatorial optimization approach for diverse motif finding applications
Background: Discovering approximately repeated patterns, or motifs, in biological sequences is an important and widely-studied problem in computational molecular biology. Most fre...
Elena Zaslavsky, Mona Singh
WABI
2010
Springer
167views Bioinformatics» more  WABI 2010»
13 years 5 months ago
Quantifying the Strength of Natural Selection of a Motif Sequence
Quantification of selective pressures on regulatory sequences is a central question in studying the evolution of gene regulatory networks. Previous methods focus primarily on sing...
Chen-Hsiang Yeang
KDD
1997
ACM
161views Data Mining» more  KDD 1997»
13 years 11 months ago
Automated Discovery of Active Motifs in Three Dimensional Molecules
In this paper 1 we present a method for discovering approximately common motifs (also known as active motifs) in three dimensional (3D) molecules. Each node in a molecule is repre...
Xiong Wang, Jason Tsong-Li Wang, Dennis Shasha, Br...
ICDM
2009
IEEE
121views Data Mining» more  ICDM 2009»
14 years 2 months ago
Finding Time Series Motifs in Disk-Resident Data
—Time series motifs are sets of very similar subsequences of a long time series. They are of interest in their own right, and are also used as inputs in several higher-level data...
Abdullah Mueen, Eamonn J. Keogh, Nima Bigdely Sham...
BMCBI
2004
111views more  BMCBI 2004»
13 years 7 months ago
Aggregation of topological motifs in the Escherichia coli transcriptional regulatory network
Background: Transcriptional regulation of cellular functions is carried out through a complex network of interactions among transcription factors and the promoter regions of genes...
Radu Dobrin, Qasim K. Beg, Albert-Lászl&oac...