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» Approximation Algorithms for Optimal RNA Secondary Structure...
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NAR
2007
124views more  NAR 2007»
13 years 7 months ago
The RNAz web server: prediction of thermodynamically stable and evolutionarily conserved RNA structures
Many non-coding RNA genes and cis-acting regulatory elements of mRNAs contain RNA secondary structures that are critical for their function. Such functional RNAs can be predicted ...
Andreas R. Gruber, Richard Neuböck, Ivo L. Ho...
BMCBI
2008
142views more  BMCBI 2008»
13 years 8 months ago
Strategies for measuring evolutionary conservation of RNA secondary structures
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...
WABI
2010
Springer
188views Bioinformatics» more  WABI 2010»
13 years 6 months ago
Prediction of RNA Secondary Structure Including Kissing Hairpin Motifs
Abstract. We present three heuristic strategies for folding RNA sequences into secondary structures including kissing hairpin motifs. The new idea is to construct a kissing hairpin...
Corinna Theis, Stefan Janssen, Robert Giegerich
BMCBI
2005
162views more  BMCBI 2005»
13 years 7 months ago
Accelerated probabilistic inference of RNA structure evolution
Background: Pairwise stochastic context-free grammars (Pair SCFGs) are powerful tools for evolutionary analysis of RNA, including simultaneous RNA sequence alignment and secondary...
Ian Holmes
JCB
2007
108views more  JCB 2007»
13 years 7 months ago
A Dynamic Programming Approach for Finding Common Patterns in RNAs
We developed a dynamic programming approach of computing common sequence structure patterns among two RNAs given their primary sequences and their secondary structures. Common pat...
Sven Siebert, Rolf Backofen