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CIBCB
2008
IEEE
14 years 3 months ago
Discovering novel cancer therapies: A computational modeling and search approach
— Solid tumors must recruit new blood vessels for growth and maintenance. Discovering drugs that block this tumor-induced development of new blood vessels (angiogenesis) is an im...
Arthur W. Mahoney, Brian G. Smith, Nicholas S. Fla...
VLDB
1987
ACM
92views Database» more  VLDB 1987»
14 years 9 days ago
Mind Your Grammar: a New Approach to Modelling Text
Beginning to create the New Oxford English Dictionary database has resulted in the realization that databases for reference texts are unlike those for conventional enterprises. Wh...
Gaston H. Gonnet, Frank Wm. Tompa
KDD
2006
ACM
113views Data Mining» more  KDD 2006»
14 years 9 months ago
A new efficient probabilistic model for mining labeled ordered trees
Mining frequent patterns is a general and important issue in data mining. Complex and unstructured (or semi-structured) datasets have appeared in major data mining applications, i...
Kosuke Hashimoto, Kiyoko F. Aoki-Kinoshita, Nobuhi...
BMCBI
2008
242views more  BMCBI 2008»
13 years 9 months ago
New time-scale criteria for model simplification of bio-reaction systems
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
Junwon Choi, Kyung-won Yang, Tai-yong Lee, Sang Yu...
AAAI
2006
13 years 10 months ago
Model Counting: A New Strategy for Obtaining Good Bounds
Model counting is the classical problem of computing the number of solutions of a given propositional formula. It vastly generalizes the NP-complete problem of propositional satis...
Carla P. Gomes, Ashish Sabharwal, Bart Selman