We compare the performance of five well-known truncation heuristics for mitigating the effects of initialization bias in the output analysis of steady-state simulations. Two of th...
K. Preston White, Michael J. Cobb, Stephen C. Spra...
Background: There is an ever increasing rate of data made available on genetic variation, transcriptomes and proteomes. Similarly, a growing variety of bioinformatic programs are ...
Erdahl T. Teber, Edward Crawford, Kent B. Bolton, ...
Background: Molecular biologists work with DNA databases that often include entire genomes. A common requirement is to search a DNA database to find exact matches for a nondegener...
There is an increasing need to automatically annotate a set of genes or proteins (from genome sequencing, DNA microarray analysis or protein 2D gel experiments) using controlled v...
Jianmin Wu, Xizeng Mao, Tao Cai, Jingchu Luo, Lipi...
Hard problems for metaheuristic search can be a source of insight for developing better methods. We examine a challenging instance of such a problem that has exactly two local opt...