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BMCBI
2011
13 years 4 months ago
ASPDock: protein-protein docking algorithm using atomic solvation parameters model
Background: Atomic Solvation Parameters (ASP) model has been proven to be a very successful method of calculating the binding free energy of protein complexes. This suggests that ...
Lin Li, Dachuan Guo, Yangyu Huang, Shiyong Liu, Yi...
BMCBI
2011
13 years 4 months ago
RedundancyMiner: De-replication of redundant GO categories in microarray and proteomics analysis
Background: The Gene Ontology (GO) Consortium organizes genes into hierarchical categories based on biological process, molecular function and subcellular localization. Tools such...
Barry Zeeberg, Hongfang Liu, Ari B. Kahn, Martin E...
BMCBI
2011
13 years 4 months ago
Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips
Background: Illumina’s Infinium SNP BeadChips are extensively used in both small and large-scale genetic studies. A fundamental step in any analysis is the processing of raw all...
Matthew E. Ritchie, Ruijie Liu, Benilton Carvalho,...
BMCBI
2011
13 years 4 months ago
LabKey Server: An open source platform for scientific data integration, analysis and collaboration
Background: Broad-based collaborations are becoming increasingly common among disease researchers. For example, the Global HIV Enterprise has united cross-disciplinary consortia t...
Elizabeth K. Nelson, Britt Piehler, Josh Eckels, A...
BMCBI
2011
13 years 4 months ago
Learning genetic epistasis using Bayesian network scoring criteria
Background: Gene-gene epistatic interactions likely play an important role in the genetic basis of many common diseases. Recently, machine-learning and data mining methods have be...
Xia Jiang, Richard E. Neapolitan, M. Michael Barma...
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