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BMCBI
2011
12 years 11 months ago
Fusion of metabolomics and proteomics data for biomarkers discovery: case study on the experimental autoimmune encephalomyelitis
Background: Analysis of Cerebrospinal Fluid (CSF) samples holds great promise to diagnose neurological pathologies and gain insight into the molecular background of these patholog...
Lionel Blanchet, Agnieszka Smolinska, Amos Attali,...
BMCBI
2011
12 years 11 months ago
Smith-Waterman Peak Alignment for Comprehensive Two-dimensional Gas Chromatography Mass Spectrometry
Background: Comprehensive two-dimensional gas chromatography coupled with mass spectrometry (GC × GCMS) is a powerful technique which has gained increasing attention over the las...
Seongho Kim, Imhoi Koo, Aiqin Fang, Xiang Zhang
BMCBI
2011
12 years 11 months ago
Study of large and highly stratified population datasets by combining iterative pruning principal component analysis and STRUCTU
Background: The ever increasing sizes of population genetic datasets pose great challenges for population structure analysis. The Tracy-Widom (TW) statistical test is widely used ...
Tulaya Limpiti, Apichart Intarapanich, Anunchai As...
BMCBI
2011
12 years 11 months ago
FFCA: a feasibility-based method for flux coupling analysis of metabolic networks
Background: Flux coupling analysis (FCA) is a useful method for finding dependencies between fluxes of a metabolic network at steady-state. FCA classifies reactions into subsets (...
László Dávid, Sayed-Amir Mara...
BMCBI
2011
12 years 11 months ago
PhyloMap: an algorithm for visualizing relationships of large sequence data sets and its application to the influenza A virus ge
Background: Results of phylogenetic analysis are often visualized as phylogenetic trees. Such a tree can typically only include up to a few hundred sequences. When more than a few...
Jiajie Zhang, Amir Madany Mamlouk, Thomas Martinet...
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