4 search results - page 1 / 1 » Aspects of coverage in medical DNA sequencing |
BMCBI
2008
13 years 11 months ago
2008
Background: DNA sequencing is now emerging as an important component in biomedical studies of diseases like cancer. Short-read, highly parallel sequencing instruments are expected...
BMCBI
2005
13 years 10 months ago
2005
Background: The allele frequencies of single-nucleotide polymorphisms (SNPs) are needed to select an optimal subset of common SNPs for use in association studies. Sequence-based m...
BMCBI
2005
13 years 10 months ago
2005
Background: The degree to which conventional DNA sequencing techniques will be successful for highly repetitive genomes is unclear. Investigators are therefore considering various...
BMCBI
2010
13 years 11 months ago
2010
Background: Mitochondrial DNA (mtDNA) is widely being used for population genetics, forensic DNA fingerprinting and clinical disease association studies. The recent past has uncov...