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» Assessing local structural perturbations in proteins
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BMCBI
2005
77views more  BMCBI 2005»
13 years 7 months ago
Structural comparison of metabolic networks in selected single cell organisms
Background: There has been tremendous interest in the study of biological network structure. An array of measurements has been conceived to assess the topological properties of th...
Dongxiao Zhu, Zhaohui S. Qin
BMCBI
2007
102views more  BMCBI 2007»
13 years 7 months ago
A comprehensive system for evaluation of remote sequence similarity detection
Background: Accurate and sensitive performance evaluation is crucial for both effective development of better structure prediction methods based on sequence similarity, and for th...
Yuan Qi, Ruslan Sadreyev, Yong Wang, Bong-Hyun Kim...
BIB
2006
141views more  BIB 2006»
13 years 7 months ago
Statistical significance in biological sequence analysis
One of the major goals of computational sequence analysis is to find sequence similarities, which could serve as evidence of structural and functional conservation, as well as of ...
Alexander Yu. Mitrophanov, Mark Borodovsky
BMCBI
2010
104views more  BMCBI 2010»
13 years 7 months ago
Parameters for accurate genome alignment
Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
Martin C. Frith, Michiaki Hamada, Paul Horton