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BMCBI
2010
158views more  BMCBI 2010»
13 years 8 months ago
Validation of differential gene expression algorithms: Application comparing fold-change estimation to hypothesis testing
Background: Sustained research on the problem of determining which genes are differentially expressed on the basis of microarray data has yielded a plethora of statistical algorit...
Corey M. Yanofsky, David R. Bickel
CIBB
2008
13 years 10 months ago
Unsupervised Stability-Based Ensembles to Discover Reliable Structures in Complex Bio-molecular Data
The assessment of the reliability of clusters discovered in bio-molecular data is a central issue in several bioinformatics problems. Several methods based on the concept of stabil...
Alberto Bertoni, Giorgio Valentini
BMCBI
2011
13 years 3 months ago
Empirical Bayesian models for analysing molecular serotyping microarrays
Background: Microarrays offer great potential as a platform for molecular diagnostics, testing clinical samples for the presence of numerous biomarkers in highly multiplexed assay...
Richard Newton, Jason Hinds, Lorenz Wernisch
SDM
2008
SIAM
157views Data Mining» more  SDM 2008»
13 years 9 months ago
ROC-tree: A Novel Decision Tree Induction Algorithm Based on Receiver Operating Characteristics to Classify Gene Expression Data
Gene expression information from microarray experiments is a primary form of data for biological analysis and can offer insights into disease processes and cellular behaviour. Suc...
M. Maruf Hossain, Md. Rafiul Hassan, James Bailey
BMCBI
2006
146views more  BMCBI 2006»
13 years 8 months ago
GeneTools - application for functional annotation and statistical hypothesis testing
Background: Modern biology has shifted from "one gene" approaches to methods for genomic-scale analysis like microarray technology, which allow simultaneous measurement ...
Vidar Beisvag, Frode K. R. Jünge, Hallgeir Be...