16 search results - page 3 / 4 » Assessment of programs for ligand binding affinity predictio... |
BMCBI
2008
13 years 7 months ago
2008
Background: Establishment of peptide binding to Major Histocompatibility Complex class I (MHCI) is a crucial step in the development of subunit vaccines and prediction of such bin...
BMCBI
2010
13 years 7 months ago
2010
Background: The binding of regulatory proteins to their specific DNA targets determines the accurate expression of the neighboring genes. The in silico prediction of new binding s...
BMCBI
2006
13 years 7 months ago
2006
Background: Many dimeric protein complexes bind cooperatively to families of bipartite nucleic acid sequence elements, which consist of pairs of conserved half-site sequences sepa...
BMCBI
2008
13 years 7 months ago
2008
Background: Virtual or in silico ligand screening combined with other computational methods is one of the most promising methods to search for new lead compounds, thereby greatly ...
BMCBI
2010
13 years 7 months ago
2010
Background: The activity of proteins within the cell is characterized by their motions, flexibility, interactions or even the particularly intriguing case of partially unfolded st...