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BMCBI
2006
134views more  BMCBI 2006»
13 years 7 months ago
A statistical score for assessing the quality of multiple sequence alignments
Background: Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein...
Virpi Ahola, Tero Aittokallio, Mauno Vihinen, Esa ...
TCBB
2010
136views more  TCBB 2010»
13 years 5 months ago
Efficient Extraction of Protein-Protein Interactions from Full-Text Articles
—Proteins and their interactions govern virtually all cellular processes, such as regulation, signaling, metabolism, and structure. Most experimental findings pertaining to such ...
Jörg Hakenberg, Robert Leaman, Nguyen Ha Vo, ...
BMCBI
2008
110views more  BMCBI 2008»
13 years 7 months ago
Enhancing the prediction of protein pairings between interacting families using orthology information
Background: It has repeatedly been shown that interacting protein families tend to have similar phylogenetic trees. These similarities can be used to predicting the mapping betwee...
José M. G. Izarzugaza, David de Juan, Carle...
BMCBI
2008
145views more  BMCBI 2008»
13 years 7 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BERTINORO
2005
Springer
14 years 29 days ago
Evolving Fractal Gene Regulatory Networks for Graceful Degradation of Software
Fractal proteins are an evolvable method of mapping genotype to phenotype through a developmental process, where genes are expressed into proteins comprised of subsets of the Mande...
Peter J. Bentley