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GECCO
2008
Springer
179views Optimization» more  GECCO 2008»
13 years 8 months ago
Evolution of discrete gene regulatory models
Gene regulatory networks (GRNs) are complex control systems that govern the interaction of genes, which ultimately control cellular processes at the protein level. GRNs can be ted...
Afshin Esmaeili, Christian Jacob
AMAI
2007
Springer
13 years 7 months ago
Reasoning about non-immediate triggers in biological networks
Modeling molecular interactions in biological networks is important from various perspectives such as predicting side effects of drugs, explaining unusual cellular behavior and dr...
Nam Tran, Chitta Baral
BMCBI
2008
57views more  BMCBI 2008»
13 years 7 months ago
A novel method for high accuracy sumoylation site prediction from protein sequences
Background: Protein sumoylation is an essential dynamic, reversible post translational modification that plays a role in dozens of cellular activities, especially the regulation o...
Jialin Xu, Yun He, Boqin Qiang, Jiangang Yuan, Xia...
ALIFE
2006
13 years 7 months ago
The Origin of the Eukaryotic Cell Based on Conservation of Existing Interfaces
Current theories about the origin of the eukaryotic cell all assume that during evolution a prokaryotic cell acquired a nucleus. Here, it is shown that a scenario in which the nucl...
Albert D. G. de Roos
BIB
2006
84views more  BIB 2006»
13 years 7 months ago
Computational methodologies for modelling, analysis and simulation of signalling networks
This article is a critical review of computational techniques used to model, analyse and simulate signalling networks. We propose a conceptual framework, and discuss the role of s...
David R. Gilbert, Hendrik Fuß, Xu Gu, Richar...