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BIOINFORMATICS
2008
119views more  BIOINFORMATICS 2008»
13 years 8 months ago
Optimal design of thermally stable proteins
Motivation: For many biotechnological purposes, it is desirable to redesign proteins to be more structurally and functionally stable at higher temperatures. For example, chemical ...
Ryan M. Bannen, Vanitha Suresh, George N. Phillips...
ICCAD
2002
IEEE
161views Hardware» more  ICCAD 2002»
14 years 4 months ago
Non-tree routing for reliability and yield improvement
We propose to introduce redundant interconnects for manufacturing yield and reliability improvement. By introducing redundant interconnects, the potential for open faults is reduc...
Andrew B. Kahng, Bao Liu, Ion I. Mandoiu
BMCBI
2006
152views more  BMCBI 2006»
13 years 7 months ago
A two-stage approach for improved prediction of residue contact maps
Background: Protein topology representations such as residue contact maps are an important intermediate step towards ab initio prediction of protein structure. Although improvemen...
Alessandro Vullo, Ian Walsh, Gianluca Pollastri
ICPP
2009
IEEE
14 years 2 months ago
Improving Resource Availability by Relaxing Network Allocation Constraints on Blue Gene/P
— High-end computing (HEC) systems have passed the petaflop barrier and continue to move toward the next frontier of exascale computing. As companies and research institutes con...
Narayan Desai, Darius Buntinas, Daniel Buettner, P...
BMCBI
2008
128views more  BMCBI 2008»
13 years 8 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson