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    » Automated modelling of signal transduction networks
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    BMCBI
    2007
    136views more  BMCBI 2007»
    Reduced modeling of signal transduction - a modular approach
    13 years 11 months ago
    Reduced modeling of signal transduction - a modular approach
    Download  www.biomedcentral.com
    Background: Combinatorial complexity is a challenging problem in detailed and mechanistic mathematical modeling of signal transduction. This subject has been discussed intensively...
    Markus Koschorreck, Holger Conzelmann, Sybille Ebe...
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    BMCBI
    2006
    122views more  BMCBI 2006»
    A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks
    13 years 11 months ago
    A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks
    Download  www.biomedcentral.com
    Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
    Holger Conzelmann, Julio Saez-Rodriguez, Thomas Sa...
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    IJON
    2006
    112views more  IJON 2006»
    Comparison of automated parameter estimation methods for neuronal signaling networks
    13 years 10 months ago
    Comparison of automated parameter estimation methods for neuronal signaling networks
    Download  sp.cs.tut.fi
    This work is a suitability study of the different optimization methods for automated parameter estimation (fitting) in the context of neuronal signaling networks. The Gepasi simul...
    Antti Pettinen, Olli Yli-Harja, Marja-Leena Linne
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    BIB
    2008
    93views more  BIB 2008»
    A structured approach for the engineering of biochemical network models, illustrated for signalling pathways
    13 years 11 months ago
    A structured approach for the engineering of biochemical network models, illustrated for signalling pathways
    Download  gbb.eldoc.ub.rug.nl
    Quantitative models of biochemical networks (signal transduction cascades, metabolic pathways, gene regulatory circuits) are a central component of modern systems biology. Buildin...
    Rainer Breitling, David Gilbert, Monika Heiner, Ri...
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    CSB
    2005
    IEEE
    163views Bioinformatics» more  CSB 2005»
    A symbolic approach to the simulation of biochemical models: application to circadian rhythms
    14 years 4 months ago
    A symbolic approach to the simulation of biochemical models: application to circadian rhythms
    Download  conferences.computer.org
    Symbolic rewriting systems are gaining interest as tools for simulating biochemical dynamics. Compared to traditional methods based on differential equations, the symbolic approac...
    Federico Fontana, Luca Bianco, Vincenzo Manca
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