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BMCBI
2005
169views more  BMCBI 2005»
13 years 7 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader
BMCBI
2005
114views more  BMCBI 2005»
13 years 7 months ago
AutoFACT: An Automatic Functional Annotation and Classification Tool
Background: Assignment of function to new molecular sequence data is an essential step in genomics projects. The usual process involves similarity searches of a given sequence aga...
Liisa B. Koski, Michael W. Gray, B. Franz Lang, Ge...
BIOINFORMATICS
2007
161views more  BIOINFORMATICS 2007»
13 years 7 months ago
Functional evaluation of domain-domain interactions and human protein interaction networks
: Large amounts of protein and domain interaction data are being produced by experimental high-throughput techniques and computational approaches. To gain insight into the value of...
Andreas Schlicker, Carola Huthmacher, Fidel Ram&ia...
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
GOPET: A tool for automated predictions of Gene Ontology terms
Background: Vast progress in sequencing projects has called for annotation on a large scale. A Number of methods have been developed to address this challenging task. These method...
Arunachalam Vinayagam, Coral del Val, Falk Schuber...
BMCBI
2004
144views more  BMCBI 2004»
13 years 7 months ago
GOtcha: a new method for prediction of protein function assessed by the annotation of seven genomes
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
David M. A. Martin, Matthew Berriman, Geoffrey J. ...