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BIOINFORMATICS
2006
142views more  BIOINFORMATICS 2006»
13 years 10 months ago
Intervention in a family of Boolean networks
Motivation: Intervention in a gene regulatory network is used to avoid undesirable states, such as those associated with a disease. Several types of intervention have been studied...
Ashish Choudhary, Aniruddha Datta, Michael L. Bitt...
GPEM
2008
128views more  GPEM 2008»
13 years 10 months ago
Coevolutionary bid-based genetic programming for problem decomposition in classification
In this work a cooperative, bid-based, model for problem decomposition is proposed with application to discrete action domains such as classification. This represents a significan...
Peter Lichodzijewski, Malcolm I. Heywood
BMCBI
2006
134views more  BMCBI 2006»
13 years 10 months ago
A statistical score for assessing the quality of multiple sequence alignments
Background: Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein...
Virpi Ahola, Tero Aittokallio, Mauno Vihinen, Esa ...
BMCBI
2006
117views more  BMCBI 2006»
13 years 10 months ago
G-InforBIO: integrated system for microbial genomics
Background: Genome databases contain diverse kinds of information, including gene annotations and nucleotide and amino acid sequences. It is not easy to integrate such information...
Naoto Tanaka, Takashi Abe, Satoru Miyazaki, Hideak...
BMCBI
2006
111views more  BMCBI 2006»
13 years 10 months ago
Tools for integrated sequence-structure analysis with UCSF Chimera
Background: Comparing related structures and viewing the structures in the context of sequence alignments are important tasks in protein structure-function research. While many pr...
Elaine C. Meng, Eric F. Pettersen, Gregory S. Couc...