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BMCBI
2011
13 years 2 days ago
A Novel And Well-Defined Benchmarking Method For Second Generation Read Mapping
Background: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almo...
Manuel Holtgrewe, Anne-Katrin Emde, David Weese, K...
BMCBI
2010
143views more  BMCBI 2010»
13 years 8 months ago
ETE: a python Environment for Tree Exploration
Background: Many bioinformatics analyses, ranging from gene clustering to phylogenetics, produce hierarchical trees as their main result. These are used to represent the relations...
Jaime Huerta-Cepas, Joaquín Dopazo, Toni Ga...
BIOINFORMATICS
2008
203views more  BIOINFORMATICS 2008»
13 years 8 months ago
The SGN comparative map viewer
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
Lukas A. Mueller, Adri A. Mills, Beth Skwarecki, R...
BIBE
2008
IEEE
14 years 3 months ago
VIP: Visualization of integrated proteomics data
—The post-genomic era is characterized by the rapid data accumulation leading to unwieldy and large volumes of biological data. The proteomics results (large sets of identified p...
Eugenia G. Giannopoulou, Giorgos Lepouras, Elias S...
RECOMB
2002
Springer
14 years 8 months ago
DNA sequence evolution with neighbor-dependent mutation
We introduce a model of DNA sequence evolution which can account for biases in mutation rates that depend on the identity of the neighboring bases. An analytic solution for this c...
Peter F. Arndt, Christopher B. Burge, Terence Hwa