Background: Mass spectrometry (MS) is an essential analytical tool in proteomics. Many existing algorithms for peptide detection are based on isotope template matching and usually...
Identifying peptides, which are short polymeric chains of amino acid residues in a protein sequence, is of fundamental importance in systems biology research. The most popular appr...
The accurate quantification of proteins is important in several areas of cell biology, biotechnology and medicine. Both relative and absolute quantification of proteins is often d...
David C. Wedge, Simon J. Gaskell, Simon J. Hubbard...
For systematic analyses of quantitative mass spectrometry data a method was developed in order to reveal peptides within a protein, that show differences in comparison with the rem...
Background: A better understanding of the mechanisms involved in gas-phase fragmentation of peptides is essential for the development of more reliable algorithms for high-throughp...