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BMCBI
2005
107views more  BMCBI 2005»
15 years 3 months ago
Identifying differential expression in multiple SAGE libraries: an overdispersed log-linear model approach
Background: In testing for differential gene expression involving multiple serial analysis of gene expression (SAGE) libraries, it is critical to account for both between and with...
Jun Lu, John K. Tomfohr, Thomas B. Kepler
BMCBI
2005
93views more  BMCBI 2005»
15 years 3 months ago
Two-part permutation tests for DNA methylation and microarray data
Background: One important application of microarray experiments is to identify differentially expressed genes. Often, small and negative expression levels were clipped-off to be e...
Markus Neuhäuser, Tanja Boes, Karl-Heinz J&ou...
BMCBI
2005
104views more  BMCBI 2005»
15 years 3 months ago
A statistical approach for array CGH data analysis
Background: Microarray-CGH experiments are used to detect and map chromosomal imbalances, by hybridizing targets of genomic DNA from a test and a reference sample to sequences imm...
Franck Picard, Stéphane Robin, Marc Laviell...
BMCBI
2005
131views more  BMCBI 2005»
15 years 3 months ago
Critical evaluation of the JDO API for the persistence and portability requirements of complex biological databases
Background: Complex biological database systems have become key computational tools used daily by scientists and researchers. Many of these systems must be capable of executing on...
Marko Srdanovic, Ulf Schenk, Michael Schwieger, Fa...
BMCBI
2005
67views more  BMCBI 2005»
15 years 3 months ago
Sequence signature analysis of chromosome identity in three Drosophila species
Background: All eukaryotic organisms need to distinguish each of their chromosomes. A few protein complexes have been described that recognise entire, specific chromosomes, for in...
Per Stenberg, Fredrik Pettersson, Anja O. Saura, A...