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BMCBI
2011
14 years 11 months ago
Bio: : Phylo - phyloinformatic analysis using Perl
Background: Phyloinformatic analyses involve large amounts of data and metadata of complex structure. Collecting, processing, analyzing, visualizing and summarizing these data and...
Rutger A. Vos, Jason Caravas, Klaas Hartmann, Mark...
BMCBI
2011
14 years 11 months ago
pROC: an open-source package for R and S+ to analyze and compare ROC curves
Background: Receiver operating characteristic (ROC) curves are useful tools to evaluate classifiers in biomedical and bioinformatics applications. However, conclusions are often r...
Xavier Robin, Natacha Turck, Alexandre Hainard, Na...
BMCBI
2011
14 years 10 months ago
Multithreaded comparative RNA secondary structure prediction using stochastic context-free grammars
Background: The prediction of the structure of large RNAs remains a particular challenge in bioinformatics, due to the computational complexity and low levels of accuracy of state...
Zsuzsanna Sukosd, Bjarne Knudsen, Morten Vaerum, J...
BMCBI
2011
14 years 10 months ago
PhyloSim - Monte Carlo simulation of sequence evolution in the R statistical computing environment
Background: The Monte Carlo simulation of sequence evolution is routinely used to assess the performance of phylogenetic inference methods and sequence alignment algorithms. Progr...
Botond Sipos, Tim Massingham, Gregory E. Jordan, N...
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BMCBI
2011
14 years 10 months ago
Properties of Metabolic Graphs: Biological Organization or Representation Artifacts?
Background: Standard graphs, where each edge links two nodes, have been extensively used to represent the connectivity of metabolic networks. It is based on this representation th...
Wanding Zhou, Luay Nakhleh